You often hear that a drug can impact your sex drive.

But most doctors don’t seem to mention it when prescribing antibiotics.

Did yours?


Some themes that have come up in session include:

used Antibiotics

Client experiences

Can antibiotics prescribed for urinary tract infections or thrush cause you to start experiencing pain during and/or after sex?

The answer appears to be yes.


pain during sex

Female Clients

I have met a number of people who describe sex as being normal and painless prior to using their prescribed medication.


Numbness during sex

Male client

Early 40s

Used antibiotics for over a month

‘My penis feels numb now. I can’t feel as much in the head.”



peripheral neuropathy

Link between the use of metronidazole and peripheral neuropathy when used for longer than 4 weeks



Metronidazole: high dose and long duration risks peripheral neuropathy


  • There is a well-established link between the use of metronidazole and peripheral neuropathy, which can be irreversible   > >


  • Peripheral neuropathy is characterised by symptoms such as numbness, loss of sensation and neuropathic pain   > >


Nitrofurantoin toxicity can peripheral neuropathy

Nitrofurantoin is an antibiotic used mainly in the treatment of urinary tract infections.


  • Skin biopsies revealed distinctive morphologic changes with clustered terminal nerve swellings without evidence of nerve fiber degeneration > >


  • Toxicity can cause peripheral neuropathy – Adverse effects > >